Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 7/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671068 | 0.78 | NOTUM (0.44) | NOTUMMGLLPOLBNPSR1TDP1 | |
| SCHEMBL2903090 | 0.78 | NOTUM (0.48) | NOTUMMGLLALDH1A1KMT2ANPC1 | |
| SCHEMBL2752440 | 0.74 | NOTUM (0.44) | NOTUMMGLLTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29094139 | 0.73 | MGLL (0.40) | MGLLPOLBTDP1ALDH1A1MEN1 | |
| SCHEMBL2760925 | 0.73 | CYP1A2 (0.46) | MGLLPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL430176 | 0.73 | GAA (0.42) | NOTUMPOLBL3MBTL1NPC1MAPT | |
| SCHEMBL27984093 | 0.72 | NOTUM (0.51) | NOTUMMGLLPOLBNPSR1ESRRA | |
| SCHEMBL7229570 | 0.71 | NOTUM (0.44) | NOTUMPOLBALDH1A1 | |
| SCHEMBL22902068 | 0.71 | NOTUM (0.50) | NOTUMMGLLPOLBNPSR1ESRRA | |
| SCHEMBL293796 | 0.70 | MGLL (0.43) | MGLLNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166015-A | Pyrrolidine derivatives-CCR-3 receptor antagonists | SYNTEX (U.S.A.) INC. (US) | 2000-12-26 | — | — | US | disclosed |