Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 4/20 | 0.64 |
| ▸ | GSK3B | P49841 | 4/20 | 0.58 |
| ▸ | PIM1 | P11309 | 4/20 | 0.58 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.58 |
| ▸ | CDC7 | O00311 | 2/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.58 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.58 |
| ▸ | CLK2 | P49760 | 2/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.58 |
| ▸ | NEK4 | P51957 | 2/20 | 0.58 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.58 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.58 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.58 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179972 | 0.95 | IGF1R (0.71) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL8172712 | 0.90 | IGF1R (0.68) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL8172711 | 0.90 | IGF1R (0.68) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL4261320 | 0.88 | PIM1 (0.73) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL8180277 | 0.83 | PIM1 (0.70) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL8180280 | 0.83 | PIM1 (0.70) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL8178435 | 0.82 | CISD1 (0.73) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL1249176 | 0.79 | IGF1R (1.00) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL1249172 | 0.79 | IGF1R (1.00) | IGF1RGSK3BPIM1PIM3PIM2 | |
| SCHEMBL15421448 | 0.79 | IGF1R (1.00) | IGF1RGSK3BPIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |