Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.70 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.70 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.70 |
| ▸ | GSK3B | P49841 | 3/20 | 0.70 |
| ▸ | CDC7 | O00311 | 3/20 | 0.70 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.70 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.70 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.70 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.70 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.70 |
| ▸ | CLK2 | P49760 | 3/20 | 0.70 |
| ▸ | GSK3A | P49840 | 3/20 | 0.70 |
| ▸ | CSNK1G2 | P78368 | 3/20 | 0.70 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.70 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.70 |
| ▸ | BRSK1 | Q8TDC3 | 3/20 | 0.70 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.70 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180277 | 1.00 | PIM1 (0.70) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL4261320 | 0.95 | PIM1 (0.73) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL8172711 | 0.88 | IGF1R (0.68) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL8172712 | 0.88 | IGF1R (0.68) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL8180686 | 0.83 | IGF1R (0.64) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL8179972 | 0.83 | IGF1R (0.71) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL15421409 | 0.82 | PIM1 (1.00) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL1248758 | 0.82 | PIM1 (1.00) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL1248757 | 0.82 | PIM1 (1.00) | PIM1PIM3PIM2GSK3BCDC7 | |
| SCHEMBL21798699 | 0.79 | XDH (0.77) | GSK3BDYRK3DYRK1ACLK4CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |