Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168628 | 1.00 | MEN1 (0.45) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL7470070 | 1.00 | MEN1 (0.45) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL7474263 | 1.00 | MEN1 (0.45) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL7479926 | 1.00 | MEN1 (0.45) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL7475006 | 0.99 | MEN1 (0.44) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL7484207 | 0.99 | MEN1 (0.44) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL7483673 | 0.96 | MEN1 (0.43) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL7473471 | 0.95 | MEN1 (0.46) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL7484229 | 0.94 | MEN1 (0.45) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL7472666 | 0.89 | ACHE (0.40) | DNM1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |