Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704000 | 0.91 | TSHR (0.38) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL21701333 | 0.73 | TSHR (0.31) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1898993 | 0.68 | — | — | |
| SCHEMBL5484576 | 0.67 | — | — | |
| SCHEMBL9096907 | 0.66 | TSHR (0.31) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7600368 | 0.65 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL27599667 | 0.65 | TDP1 (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL3854565 | 0.65 | — | — | |
| SCHEMBL11790920 | 0.65 | — | — | |
| SCHEMBL28229242 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |