Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186473 | 0.85 | HTR2C (0.39) | KMT2AMEN1L3MBTL1HTR1AHTR7 | |
| SCHEMBL7647993 | 0.83 | NAMPT (0.36) | KMT2AMEN1TSHRMMP3MMP8 | |
| SCHEMBL7652613 | 0.78 | MEN1 (0.34) | KMT2AMEN1MAPT | |
| SCHEMBL7650642 | 0.77 | NAPRT (0.40) | HSD17B10PKMHTR1AHTR7LMNA | |
| SCHEMBL7966114 | 0.76 | KMT2A (0.53) | KMT2AMEN1MMP8MMP2LMNA | |
| SCHEMBL7647370 | 0.73 | TSHR (0.47) | KMT2AMEN1TSHRMAPK1HSD17B10 | |
| SCHEMBL1899031 | 0.68 | TP53 (0.52) | KMT2ATSHRMAPK1HSD17B10MMP8 | |
| SCHEMBL2632802 | 0.65 | MEN1 (0.50) | KMT2AMEN1MAPT | |
| SCHEMBL19201578 | 0.64 | MMP1 (0.50) | KMT2AMEN1TSHRMAPK1HSD17B10 | |
| SCHEMBL24817130 | 0.64 | SMN1; SMN2 (0.52) | KMT2AMEN1HSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000000472-A1 | 5-HT7 RECEPTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |