Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.48 |
| ▸ | RECQL | P46063 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | APEX1 | P27695 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | MITF | O75030 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181542 | 1.00 | F2 (0.56) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL8172539 | 0.94 | F2 (0.62) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL8190580 | 0.75 | POLB (0.57) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL8190582 | 0.75 | POLB (0.57) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL1065724 | 0.71 | F2 (1.00) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL1704746 | 0.71 | F2 (1.00) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL13024523 | 0.71 | F2 (1.00) | F2MEN1KMT2ARECQLMAPT | |
| SCHEMBL8182589 | 0.70 | GSK3B (0.43) | — | |
| SCHEMBL8182951 | 0.70 | PIM1 (0.48) | F2MAPTKDM4ETDP1MAPK1 | |
| SCHEMBL9298131 | 0.70 | F2 (0.67) | F2MEN1KMT2ARECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |