Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181713 | 1.00 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8190952 | 1.00 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8622047 | 0.86 | — | — | |
| SCHEMBL8194316 | 0.85 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL9274702 | 0.84 | MMP1 (0.32) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL10860789 | 0.82 | MMP1 (0.31) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8232561 | 0.79 | TDP1 (0.33) | TDP1 | |
| SCHEMBL5173272 | 0.79 | — | — | |
| SCHEMBL4971574 | 0.79 | — | — | |
| SCHEMBL10860504 | 0.78 | SLC1A3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618213-B1 | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0618213-A1 | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1994-10-05 | — | — | EP | disclosed |