Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598350 | 0.86 | HCRTR1 (0.39) | HCRTR1HCRTR2SMN1; SMN2TSHRCYP26A1 | |
| SCHEMBL598349 | 0.86 | HCRTR1 (0.39) | HCRTR1HCRTR2SMN1; SMN2TSHRCYP26A1 | |
| SCHEMBL598931 | 0.85 | BRD4 (0.42) | HCRTR1HCRTR2SMN1; SMN2TSHRCYP26A1 | |
| SCHEMBL598932 | 0.85 | BRD4 (0.42) | HCRTR1HCRTR2SMN1; SMN2TSHRCYP26A1 | |
| SCHEMBL3395450 | 0.84 | CYP26A1 (0.42) | HCRTR1HCRTR2SMN1; SMN2TSHRCYP26A1 | |
| SCHEMBL3395452 | 0.84 | CYP26A1 (0.42) | HCRTR1HCRTR2SMN1; SMN2TSHRCYP26A1 | |
| SCHEMBL598705 | 0.83 | KLK7 (0.45) | HCRTR1HCRTR2DPP4 | |
| SCHEMBL598704 | 0.83 | KLK7 (0.45) | HCRTR1HCRTR2DPP4 | |
| SCHEMBL13717031 | 0.81 | ABCB1 (0.44) | SMN1; SMN2CYP26A1RAB9ACCR5MEN1 | |
| SCHEMBL12518938 | 0.81 | ABCB1 (0.44) | SMN1; SMN2CYP26A1RAB9ACCR5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083967-A2 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2008-07-17 | — | — | WO | disclosed |