Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181790 | 1.00 | PTGS2 (0.51) | PTGS2PTGS1TDP1GAAMEN1 | |
| SCHEMBL7704839 | 0.82 | PTGS2 (0.75) | PTGS2PTGS1GAAMEN1ALDH1A1 | |
| SCHEMBL7701753 | 0.82 | PTGS2 (0.75) | PTGS2PTGS1GAAMEN1ALDH1A1 | |
| SCHEMBL8179956 | 0.75 | PTGS2 (0.69) | PTGS2PTGS1GAAMEN1ALDH1A1 | |
| SCHEMBL8179957 | 0.75 | PTGS2 (0.69) | PTGS2PTGS1GAAMEN1ALDH1A1 | |
| SCHEMBL8492533 | 0.70 | PTGS2 (0.51) | PTGS2PTGS1GAAMEN1KMT2A | |
| SCHEMBL6612658 | 0.70 | TYR (0.58) | — | |
| SCHEMBL6611853 | 0.70 | TYR (0.58) | — | |
| SCHEMBL8188183 | 0.69 | MEN1 (0.54) | PTGS2PTGS1GAAMEN1ALDH1A1 | |
| SCHEMBL8186884 | 0.69 | TDP1 (0.50) | TDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |