Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705694 | 1.00 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL7664651 | 1.00 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL27451111 | 1.00 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL16705700 | 1.00 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL11175669 | 1.00 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL5694255 | 0.98 | THRB (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL8170418 | 0.95 | TSHR (0.56) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL11177318 | 0.95 | THRB (0.61) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL14346689 | 0.94 | THRB (0.56) | TSHRALDH1A1CYP3A4THRBNR5A1 | |
| SCHEMBL19621629 | 0.93 | TSHR (0.53) | TSHRALDH1A1CYP3A4THRBNR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| EP-0520281-B1 | Optical element for generating short wave laser light | HOFFMANN LA ROCHE (CH) | 1997-03-12 | — | — | EP | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0520281-A2 | Optical element for generating short wave laser light | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-30 | — | — | EP | disclosed |