Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.47 |
| ▸ | TCF7L2 | Q9NQB0 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185671 | 0.91 | CYP1A2 (0.53) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL8179531 | 0.89 | CTNNB1 (0.47) | CTNNB1TCF7L2MAPTLMNAMEN1 | |
| SCHEMBL8178012 | 0.88 | PRKCI (0.49) | CTNNB1TCF7L2MAPTLMNAMEN1 | |
| SCHEMBL8176754 | 0.87 | CTNNB1 (0.45) | CTNNB1TCF7L2MAPTLMNAMEN1 | |
| SCHEMBL8178957 | 0.87 | MEN1 (0.53) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL8179480 | 0.87 | CLK4 (0.41) | FLT3CTNNB1TCF7L2MAPTLMNA | |
| SCHEMBL8177976 | 0.86 | CTNNB1 (0.44) | CTNNB1TCF7L2MAPTLMNAMEN1 | |
| SCHEMBL8179358 | 0.85 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL8185117 | 0.84 | HSD17B10 (0.50) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL5129501 | 0.83 | PRKCI (0.50) | FLT3MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |