Ribitol

Ribitol

SCHEMBL8182152

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.83
L3MBTL1 Q9Y468 1/20 0.83
TDP1 Q9NUW8 2/20 0.77
KDM4E B2RXH2 2/20 0.50
PDE4A P27815 1/20 0.50
USP2 O75604 1/20 0.46
SLCO1B1 Q9Y6L6 1/20 0.46
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xylitol SCHEMBL13080875 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL4599492 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL5306386 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL8749454 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL5273838 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Adonitol SCHEMBL20594035 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL1924966 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Adonitol SCHEMBL22572531 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL20594034 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL16627357 1.00 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6075059-A COMPRISING WATER, A LOCAL ANESTHETIC AGENT, AND A SUGAR ALCOHOL THE OHIO STATE UNIVERSITY (US) 2000-06-13 US claimed
CN-116261597-A Production of Fuc-a1,2-Gal-R in the alpha-1, 3 glycosylated form 因比奥斯公司 2023-06-13 CN disclosed
US-11059835-B2 Synthesis of cephalosporin compounds MERCK SHARP & DOHME CORP. (US) 2021-07-13 US disclosed
US-20200385404-A1 SYNTHESIS OF CEPHALOSPORIN COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2020-12-10 US disclosed
EP-3727652-A1 SYNERGIZED ACETALS COMPOSITION AND METHOD FOR SCAVENGING SULFIDES AND MERCAPTANTS Clariant International Ltd (CH) 2020-10-28 EP disclosed
WO-2018182774-A1 HERBICIDE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2018-10-04 WO disclosed
EP-2872110-A2 COSMETIC COMPOSITION COMPRISING BENZYLSULFONYL-D-SER-HOMOPHE-(4-AMIDINO-BENZYLAMIDE) AND A POLYALCOHOL DSM IP Assets B.V. (NL) 2015-05-20 EP disclosed
WO-2014009862-A2 COSMETIC COMPOSITION COMPRISING BENZYLSULFONYL-D-SER-HOMOPHE-(4-AMIDINO-BENZYLAMIDE) AND A POLYALCOHOL DSM IP ASSETS B.V. (NL) 2014-01-16 WO disclosed
US-6075059-A COMPRISING WATER, A LOCAL ANESTHETIC AGENT, AND A SUGAR ALCOHOL THE OHIO STATE UNIVERSITY (US) 2000-06-13 US disclosed
US-4371656-A Metal substituted zeolites as stabilizers for halogen-containing resins NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 1983-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200385404-A1 SYNTHESIS OF CEPHALOSPORIN COMPOUNDS COASY, DDT, PEPD LMNA 4633/4885L3MBTL1 4445/4885TDP1 4243/4885
US-11059835-B2 Synthesis of cephalosporin compounds COASY, DDT, PEPD LMNA 4633/4885L3MBTL1 4445/4885TDP1 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.