Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819970 | 0.99 | ALDH1A1 (0.46) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL819466 | 0.96 | TSHR (0.43) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL817510 | 0.90 | ALDH1A1 (0.42) | TSHRALDH1A1LMNAESR1CHRM2 | |
| SCHEMBL819216 | 0.85 | MAPT (0.42) | TSHRCYP3A4MAPK1ALDH1A1LMNA | |
| SCHEMBL817353 | 0.80 | ALDH1A1 (0.51) | TSHRCYP3A4MAPK1ALDH1A1LMNA | |
| SCHEMBL819151 | 0.78 | TSHR (0.48) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL818466 | 0.77 | ALDH1A1 (0.41) | TSHRALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL9863046 | 0.77 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL16732318 | 0.77 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL8975464 | 0.77 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |