SCHEMBL818324

SCHEMBL818324

CCCCCC(N)CCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.56
S1PR2 O95136 5/20 0.53
S1PR1 P21453 5/20 0.53
S1PR3 Q99500 5/20 0.53
S1PR4 O95977 4/20 0.53
TP53 P04637 2/20 0.50
CYP2D6 P10635 2/20 0.48
SPHK1 Q9NYA1 2/20 0.48
LMNA P02545 2/20 0.48
PLA2G1B P04054 1/20 0.48
PLA2G2A P14555 1/20 0.48
GMNN O75496 1/20 0.48
POLB P06746 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48
BLM P54132 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL817899 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL8686837 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL10822877 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL8688414 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL3395218 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL8054198 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL3962483 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL6321434 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL9184259 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4
SCHEMBL818216 0.98 S1PR2 (0.57) OPRM1S1PR2S1PR1S1PR3S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39530-E1 3-amino-3-arylpropan-1-ol-compounds, their preparation and use GRUENENTHAL GMBH (DE) 2007-03-27 US claimed
US-7105628-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2006-09-12 US claimed
US-20040220378-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US claimed
EP-1043306-B1 3-amino-3-arylpropan-1-ol-derivates, their preparation and use GRUENENTHAL GMBH (DE) 2004-03-31 EP claimed
EP-1043307-B1 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use GRUENENTHAL GMBH (DE) 2003-06-04 EP claimed
US-6410790-B1 ANALGESICS GRUENENTHAL GMBH (DE) 2002-06-25 US claimed
US-6288278-B1 BENZENE DERIVED AMINO ALCOHOLS AS DRUGS GRUENENTHAL GMBH (DE) 2001-09-11 US claimed
US-20220403530-A1 METHOD FOR POLISHING PARTS MADE OF ALUMINUM ACONDICIONAMIENTO TARRASENSE (ES) 2022-12-22 US disclosed
EP-4060080-A1 METHOD FOR POLISHING PARTS MADE OF ALUMINUM Acondicionamiento Tarrasense (ES) 2022-09-21 EP disclosed
EP-3423554-B1 LUBRICATING OIL COMPOSITION HAVING IMPROVED AIR RELEASE LUBRIZOL CORP (US) 2022-08-10 EP disclosed
CN-109072122-B Lubricating oil composition with improved air release 路博润公司 2022-03-04 CN disclosed
WO-2021094641-A1 METHOD FOR POLISHING PARTS MADE OF ALUMINUM ACONDICIONAMIENTO TARRASENSE (ES) 2021-05-20 WO disclosed
EP-3822392-A1 METHOD FOR POLISHING PARTS MADE OF ALUMINUM ALLOYS COMPRISING SILICON Acondicionamiento Tarrasense (ES) 2021-05-19 EP disclosed
WO-1991014041-A1 TREATED POLYMER FABRICS THE LUBRIZOL CORPORATION (US) 1991-09-19 WO disclosed
WO-1991009922-A1 UNIVERSAL DRIVELINE FLUIDE THE LUBRIZOL CORPORATION (US) 1991-07-11 WO disclosed
US-4992184-A Reaction product of arylsulfonic acid and (diol or amine) phosphite MOBIL OIL CORPORATION (US) 1991-02-12 US disclosed
US-4965002-A Reaction product of alkoxylated amine and organic phosphize ELCO CORPORATION (US) 1990-10-23 US disclosed
EP-0309486-A1 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS The Lubrizol Corporation (US) 1989-04-05 EP disclosed
US-4755311-A Borated amine salt of dihydrocarbyl monothiophosphoric acid THE LUBRIZOL CORPORATION (US) 1988-07-05 US disclosed
WO-1987007638-A2 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed