SCHEMBL817899

SCHEMBL817899

CCCCCCCC(N)CCO

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 5/20 0.57
S1PR1 P21453 5/20 0.57
S1PR3 Q99500 5/20 0.57
S1PR4 O95977 4/20 0.57
OPRM1 P35372 1/20 0.54
LMNA P02545 4/20 0.52
CYP2D6 P10635 2/20 0.52
SPHK1 Q9NYA1 2/20 0.52
TP53 P04637 2/20 0.52
PLA2G1B P04054 1/20 0.52
PLA2G2A P14555 1/20 0.52
GMNN O75496 1/20 0.52
POLB P06746 1/20 0.52
THPO P40225 1/20 0.52
MTOR P42345 1/20 0.52
BLM P54132 1/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686906 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL10822877 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL3962483 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL3395218 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL6321434 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL8686837 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL8054198 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL9184259 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL8688414 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL818216 1.00 S1PR2 (0.57) S1PR2S1PR1S1PR3S1PR4OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105628-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2006-09-12 US claimed
US-20040220378-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US claimed
US-4529528-A Reacting an alkoxylated amine and a phosphite MOBIL OIL CORPORATION (US) 1985-07-16 US claimed
US-20230011118-A1 INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMACEUTICALS INCORPORATED 2023-01-12 US disclosed
EP-3423554-B1 LUBRICATING OIL COMPOSITION HAVING IMPROVED AIR RELEASE LUBRIZOL CORP (US) 2022-08-10 EP disclosed
US-20200318027-A1 Lubricating Oil Composition Having Improved Air Release LUBRIZOL CORP (US) 2020-10-08 US disclosed
EP-3423554-A1 LUBRICATING OIL COMPOSITION HAVING IMPROVED AIR RELEASE The Lubrizol Corporation (US) 2019-01-09 EP disclosed
US-9433827-B2 Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance ACUSHNET COMPANY (US) 2016-09-06 US disclosed
US-20150072807-A1 GOLF EQUIPMENT FORMED FROM CASTABLE FORMULATION WITH UNCONVENTIONALLY LOW HARDNESS AND INCREASED SHEAR RESISTANCE ACUSHNET COMPANY (US) 2015-03-12 US disclosed
US-8907040-B2 Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance ACUSHNET COMPANY (US) 2014-12-09 US disclosed
US-20130137537-A1 GOLF EQUIPMENT FORMED FROM CASTABLE FORMULATION WITH UNCONVENTIONALLY LOW HARDNESS AND INCREASED SHEAR RESISTANCE ACUSHNET COMPANY (US) 2013-05-30 US disclosed
US-4992184-A Reaction product of arylsulfonic acid and (diol or amine) phosphite MOBIL OIL CORPORATION (US) 1991-02-12 US disclosed
US-4965002-A Reaction product of alkoxylated amine and organic phosphize ELCO CORPORATION (US) 1990-10-23 US disclosed
EP-0325977-A1 Phosphite amine lubricant additives THE ELCO CORPORATION (US) 1989-08-02 EP disclosed
EP-0309486-A1 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS The Lubrizol Corporation (US) 1989-04-05 EP disclosed
US-4755311-A Borated amine salt of dihydrocarbyl monothiophosphoric acid THE LUBRIZOL CORPORATION (US) 1988-07-05 US disclosed
WO-1987007638-A2 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed
US-4557845-A FRICTION REDUCERS AND FUEL CONSUMPTION REDUCERS MOBIL OIL CORPORATION (US) 1985-12-10 US disclosed
US-4529528-A Reacting an alkoxylated amine and a phosphite MOBIL OIL CORPORATION (US) 1985-07-16 US disclosed
US-3972890-A ACID CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230011118-A1 INHIBITORS OF APOL1 AND METHODS OF USING SAME APOL1, APOB, SAAL1 S1PR2 625/4885S1PR1 553/4885S1PR3 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.