Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818403 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL818849 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL8624116 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL817954 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL31608768 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL670833 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL10638818 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL818563 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL818542 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL817791 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |