SCHEMBL818384

SCHEMBL818384

C/C(=C/C1CN1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.56
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
BRD4 O60885 2/20 0.35
CREBBP Q92793 2/20 0.35
CHRM3 P20309 1/20 0.34
DEGS1 O15121 1/20 0.34
NPC1 O15118 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GRIK2 Q13002 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6611353 0.81 SLC6A3 (0.49) KDM1A
SCHEMBL13729451 0.73 KDM1A (0.55) KDM1ACES2CES1BRD4CREBBP
SCHEMBL816885 0.73 KDM1A (0.42) KDM1ACYP1A2GRIK2
SCHEMBL817420 0.73 KDM1A (0.50) KDM1ACHRM3
SCHEMBL817793 0.72 KDM1A (0.45) KDM1A
SCHEMBL18173412 0.72 KDM1A (1.00) KDM1ACES2CES1CHRM3CYP1A2
SCHEMBL18173410 0.72 KDM1A (1.00) KDM1ACES2CES1CHRM3CYP1A2
SCHEMBL10842594 0.71 KDM1A (0.52) KDM1ACES2CES1BRD4CREBBP
Hydrochloric Acid SCHEMBL18172775 0.71 KDM1A (0.96) KDM1ACES2CES1CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL18172772 0.71 KDM1A (0.96) KDM1ACES2CES1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275756-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-10 US disclosed