Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 10/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206794 | 1.00 | LMNA (0.53) | LMNAADKBCHEMAOBP2RY6 | |
| SCHEMBL7205865 | 0.98 | LMNA (0.53) | LMNAADKBCHEMAOBP2RY6 | |
| SCHEMBL8193230 | 0.98 | LMNA (0.53) | LMNAADKBCHEMAOBP2RY6 | |
| SCHEMBL7206423 | 0.96 | LMNA (0.54) | LMNAADKBCHEMAOBP2RY6 | |
| SCHEMBL8198393 | 0.96 | LMNA (0.54) | LMNAADKBCHEMAOBP2RY6 | |
| SCHEMBL3825870 | 0.87 | LMNA (0.60) | LMNAADKP2RY6 | |
| SCHEMBL7209492 | 0.86 | LMNA (0.55) | LMNAADK | |
| SCHEMBL8184942 | 0.86 | LMNA (0.55) | LMNAADK | |
| SCHEMBL7206447 | 0.86 | LMNA (0.49) | LMNAADK | |
| SCHEMBL3820963 | 0.85 | LMNA (0.66) | LMNAADKP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| US-6005098-A | 5'deoxycytidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |