Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DCK | P27707 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639426 | 0.84 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8180602 | 0.77 | RAB9A (0.43) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8125293 | 0.77 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8140494 | 0.76 | RAB9A (0.77) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8133558 | 0.76 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1KDM4ELMNA | |
| SCHEMBL8132161 | 0.76 | RAB9A (0.41) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8134849 | 0.75 | CYP1A2 (0.55) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL8138707 | 0.74 | RAB9A (0.73) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8126631 | 0.74 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8141599 | 0.74 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124306-A | Thioalkyl alpha substituted pyrimidine compounds | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999019304-A9 | ALPHA-ALKYLTHIO SUBSTITUTED PYRIMIDINE ETHERS AND THIOETHERS AS VIRAL REVERSE TRANSCRIPTASE INHIBITORS | UPJOHN CO (US) | 1999-07-08 | — | — | WO | disclosed |