Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182076 | 0.92 | MEN1 (0.54) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8179259 | 0.91 | PDE5A (0.55) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8184297 | 0.90 | PDE5A (0.59) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8180049 | 0.90 | PDE5A (0.59) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8177662 | 0.89 | PDE5A (0.57) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL5128123 | 0.88 | PDE5A (0.60) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8177295 | 0.88 | PDE5A (0.56) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8185246 | 0.86 | MEN1 (0.45) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8179818 | 0.85 | FYN (0.44) | PDE5AMEN1KMT2AMAPTPOLB | |
| SCHEMBL8180899 | 0.85 | MEN1 (0.52) | PDE5AMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |