Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.86 |
| ▸ | CYCS | P99999 | 4/20 | 0.83 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392584 | 1.00 | TOP1 (0.86) | TOP1CYCSENPP2ABCG2MAPK14 | |
| Porphirin SCHEMBL29373094 | 1.00 | TOP1 (0.86) | TOP1CYCSENPP2ABCG2MAPK14 | |
| Hydrochloric Acid SCHEMBL31307090 | 0.93 | TOP1 (0.94) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL29354037 | 0.93 | TOP1 (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL709532 | 0.93 | TOP1 (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL1497141 | 0.91 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL17183606 | 0.91 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT | |
| Hydrochloric Acid SCHEMBL17002623 | 0.91 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL3047596 | 0.91 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL19640853 | 0.91 | CYCS (1.00) | TOP1CYCSENPP2ABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087493-A | ENZYME IHIBITORS | REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0988037-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998033503-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-08-06 | — | — | WO | disclosed |