SCHEMBL8185448

SCHEMBL8185448

O=Cc1ccc(CO)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL405828 0.88 MAPT (0.50)
SCHEMBL8570131 0.86 DPP4 (0.51)
SCHEMBL3229983 0.83 ALDH1A1 (0.39)
SCHEMBL29020313 0.81 ALDH1A1 (0.44)
SCHEMBL16901837 0.79 ALDH1A1 (0.37)
SCHEMBL7993700 0.77
SCHEMBL12664443 0.77 ALDH1A1 (0.41)
SCHEMBL158329 0.77
SCHEMBL30762026 0.77
SCHEMBL18511309 0.77 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118124-A Nitrogen-rich DOPO-based flame retardant, synthesis and application thereof 常州大学 2025-06-10 CN claimed
US-10662142-B2 Process for production of aromatic compounds comprising at least two amine functions RHODIA OPERATIONS (FR) 2020-05-26 US claimed
US-20190292128-A1 PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS SPECIALTY OPERATIONS FRANCE (FR) 2019-09-26 US claimed
CN-120118124-A Nitrogen-rich DOPO-based flame retardant, synthesis and application thereof 常州大学 2025-06-10 CN disclosed
US-12037531-B2 Photoresponsive high-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2024-07-16 US disclosed
CN-115057836-B Ester compound and preparation method and application thereof 浙江糖能科技有限公司 2023-11-28 CN disclosed
CN-114656431-B Alpha, beta-unsaturated ketone compound, and preparation method and application thereof 浙江糖能科技有限公司 2023-11-28 CN disclosed
US-11643579-B2 Adhesive composition comprising a phosphate salt and a thermosetting resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-05-09 US disclosed
US-11643579-B2 Adhesive composition comprising a phosphate salt and a thermosetting resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-05-09 US disclosed
CN-115057836-A Ester compound and preparation method and application thereof 浙江糖能科技有限公司 2022-09-16 CN disclosed
CN-114656431-A Alpha, beta-unsaturated ketone compound and preparation method and application thereof 浙江糖能科技有限公司 2022-06-24 CN disclosed
US-20190292128-A1 PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS SPECIALTY OPERATIONS FRANCE (FR) 2019-09-26 US disclosed
WO-2018015674-A1 HIGH-STRENGTH RUBBER COMPOSITION COMPRISING A DERIVATIVE OF A PHENOL COMPOUND COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-01-25 WO disclosed
WO-2017168109-A1 AQUEOUS ADHESIVE COMPOSITION COMPRISING A THERMOSETTING RESIN COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-10-05 WO disclosed
WO-2017168107-A1 AQUEOUS ADHESIVE COMPOSITION COMPRISING A THERMOSETTING RESIN AND A LATEX COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-10-05 WO disclosed
CN-103992310-B One group replaces benzo heterocyclic amine derivant and preparation method thereof and the related application as IMPDH inhibitor 中国医学科学院医药生物技术研究所 2016-07-06 CN disclosed
CN-103992310-A Group of substituted benzoheterocycle amine derivatives and preparation method and related application thereof as IMPDH (inosine monophosphate dehydrogenase) inhibitor INST MEDICINAL BIOTECHNOLOGY 2014-08-20 CN disclosed
WO-2010140685-A1 HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER 日産化学工業株式会社 (JP) 2010-12-09 WO disclosed
WO-2000032598-A9 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISEASES UTILIZING INHIBITORS OF TUMOR NECROSIS FACTOR ACTIVITY STRUCTURAL BIOINFORMATICS INC (US) 2000-11-30 WO disclosed
WO-2000032598-A1 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISEASES UTILIZING INHIBITORS OF TUMOR NECROSIS FACTOR ACTIVITY STRUCTURAL BIOINFORMATICS INC. (US) 2000-06-08 WO disclosed