Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186132 | 0.84 | KMT2A (0.49) | MAPTTSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL31305912 | 0.81 | PTPRC (0.50) | PTPRCSLC6A3MAPTTSHRMEN1 | |
| SCHEMBL7406575 | 0.81 | PTPRC (0.50) | PTPRCSLC6A3MAPTTSHRMEN1 | |
| SCHEMBL13728618 | 0.78 | PTPRC (0.48) | PTPRCSLC6A3MAPTTSHRMEN1 | |
| SCHEMBL5886388 | 0.78 | PTPRC (0.48) | PTPRCSLC6A3MAPTTSHRMEN1 | |
| SCHEMBL14178911 | 0.75 | PTPRC (0.51) | PTPRCSLC6A3MAPTTSHRMITF | |
| SCHEMBL70284 | 0.73 | MAPT (0.67) | PTPRCSLC6A3MAPTTSHRMITF | |
| SCHEMBL12764964 | 0.72 | PIM1 (0.44) | MAPTHTTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL12466684 | 0.72 | MAP2K1 (0.41) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8180609 | 0.71 | DRD2 (0.44) | SLC6A3MAPTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087399-A | ANTIULCER AGENTS; CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-07-11 | — | — | US | disclosed |