SCHEMBL8185809

SCHEMBL8185809

CCCCC=CC(O)CCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CYP3A4 P08684 1/20 0.46
SPHK2 Q9NRA0 4/20 0.44
SPHK1 Q9NYA1 4/20 0.44
CETP P11597 3/20 0.44
MAPT P10636 5/20 0.44
TRPA1 O75762 1/20 0.44
DDAH1 O94760 1/20 0.44
GAPDH P04406 1/20 0.44
PPARG P37231 2/20 0.44
GPR132 Q9UNW8 1/20 0.44
GMNN O75496 2/20 0.43
LMNA P02545 2/20 0.43
GLA P06280 2/20 0.43
POLB P06746 2/20 0.43
THRB P10828 2/20 0.43
MAPK1 P28482 2/20 0.43
CXCR5 P32302 2/20 0.43
CCR6 P51684 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8185806 1.00 MEN1 (0.46) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL10673357 0.91 MEN1 (0.56) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL10673354 0.91 MEN1 (0.56) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL7124766 0.87 SPHK2 (0.46) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL11698085 0.87 PPARG (0.57) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL7118583 0.87 SPHK2 (0.42) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL7124765 0.87 SPHK2 (0.46) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL7118580 0.87 SPHK2 (0.42) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL19628508 0.86 TAS1R3 (0.39) MEN1KMT2ACYP3A4SPHK2SPHK1
SCHEMBL18669173 0.86 TAS1R3 (0.39) MEN1KMT2ACYP3A4SPHK2SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1958630-A Method for preparing polyacrylate, and fluorin modified polyacrylate obtained from the method WANG ZHIJUN (CN) 2007-05-09 CN disclosed
US-6048991-A Preparation of epoxides BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
US-5916430-A Preparation of epoxides BASF AKTIENGESELLSCHAFT (DE) 1999-06-29 US disclosed
EP-0485783-B1 Process for producing epoxy compounds BASF AG (DE) 1995-01-11 EP disclosed
EP-0485783-A2 Process for producing epoxy compounds BASF Aktiengesellschaft (DE) 1992-05-20 EP disclosed