Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.67 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.38 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185990 | 1.00 | TGFBR1 (0.67) | TGFBR1FPR2NOD1CHRM1AKR1A1 | |
| SCHEMBL8187236 | 0.89 | TGFBR1 (0.62) | TGFBR1NOD1HDAC2MMEFOLH1 | |
| SCHEMBL5940625 | 0.89 | TGFBR1 (0.62) | TGFBR1NOD1HDAC2MMEFOLH1 | |
| SCHEMBL2831733 | 0.86 | TGFBR1 (0.59) | TGFBR1NOD1FOLH1MAPTPLA2G2A | |
| SCHEMBL4613393 | 0.86 | TGFBR1 (0.59) | TGFBR1NOD1FOLH1MAPTPLA2G2A | |
| SCHEMBL4442415 | 0.84 | TGFBR1 (0.71) | TGFBR1MMEFOLH1NAALAD2KDM4E | |
| SCHEMBL1556930 | 0.83 | TGFBR1 (0.65) | TGFBR1FOLH1RIMKLANAALAD2 | |
| SCHEMBL1556929 | 0.83 | TGFBR1 (0.65) | TGFBR1FOLH1RIMKLANAALAD2 | |
| Ammonia Solution, Strong SCHEMBL18140275 | 0.81 | TGFBR1 (0.62) | TGFBR1FOLH1RIMKLANAALAD2 | |
| Ammonia Solution, Strong SCHEMBL18140383 | 0.81 | TGFBR1 (0.62) | TGFBR1FOLH1RIMKLANAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046289-A | FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS | FUJIFILM CORPORATION (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0488258-B1 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0488258-A2 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |