Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819817 | 0.82 | TSHR (0.36) | TSHRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL817439 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL818971 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL818575 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL817269 | 0.69 | ALDH1A1 (0.39) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL819233 | 0.67 | ALDH1A1 (0.40) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL818845 | 0.66 | TSHR (0.49) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL27496718 | 0.66 | TSHR (0.38) | TSHRALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL818284 | 0.65 | ALDH1A1 (0.38) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL818658 | 0.65 | ALDH1A1 (0.38) | TSHRALDH1A1CACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |