Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.53 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727457 | 0.74 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL3724429 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MITF | |
| SCHEMBL4237634 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MITF | |
| SCHEMBL10413244 | 0.71 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL6926417 | 0.71 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL14920544 | 0.71 | SLC6A4 (0.65) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL22285003 | 0.71 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL29022140 | 0.71 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL10388380 | 0.71 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL3447412 | 0.71 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153611-A | AS NON-DOPAMINERGIC ANTIISCHEMIC COMPOUNDS FOR TREATING BRAIN DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-11-28 | — | — | US | disclosed |