Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184526 | 0.91 | PRKCI (0.46) | PRKCIPDE5A | |
| SCHEMBL8181051 | 0.90 | PRKCI (0.51) | PRKCIALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL8170976 | 0.90 | CA1 (0.47) | PRKCIMAPTALDH1A1LMNATP53 | |
| SCHEMBL5122356 | 0.84 | PRKCI (0.60) | PRKCIPDE5AKDM4EGAA | |
| SCHEMBL8180286 | 0.84 | CNR2 (0.42) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8184338 | 0.84 | CNR2 (0.42) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8187376 | 0.83 | MGLL (0.44) | PRKCIMGLLMAPTALDH1A1LMNA | |
| SCHEMBL8180529 | 0.82 | PDE5A (0.47) | PRKCIMGLLMAPTALDH1A1LMNA | |
| SCHEMBL8185543 | 0.82 | KDM4E (0.47) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8171294 | 0.81 | PRKCI (0.53) | PRKCIALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |