Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.71 |
| ▸ | PIM1 | P11309 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 15/20 | 0.58 |
| ▸ | PNP | P00491 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186306 | 1.00 | GSK3B (0.71) | GSK3BPIM1TDP1PNPHTT | |
| SCHEMBL1250017 | 0.83 | GSK3B (1.00) | GSK3BPIM1TDP1HTTNPC1 | |
| SCHEMBL1250019 | 0.83 | GSK3B (1.00) | GSK3BPIM1TDP1HTTNPC1 | |
| SCHEMBL8178919 | 0.77 | PIM1 (1.00) | GSK3BPIM1TDP1HTTNPC1 | |
| SCHEMBL8176936 | 0.77 | PIM1 (1.00) | GSK3BPIM1TDP1HTTNPC1 | |
| SCHEMBL2685792 | 0.76 | TDP1 (0.70) | PIM1TDP1PNP | |
| SCHEMBL2685789 | 0.76 | TDP1 (0.70) | PIM1TDP1PNP | |
| SCHEMBL19546477 | 0.76 | TDP1 (0.70) | PIM1TDP1PNP | |
| SCHEMBL14860992 | 0.73 | TDP1 (1.00) | GSK3BTDP1PNPRAB9AMEN1 | |
| SCHEMBL14860991 | 0.73 | TDP1 (1.00) | GSK3BTDP1PNPRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |