Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL503943 | 1.00 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL19704478 | 1.00 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL2349922 | 1.00 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28100151 | 0.96 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL66882 | 0.96 | — | — | |
| Succinic Acid SCHEMBL1335834 | 0.96 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL22471655 | 0.96 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL504448 | 0.92 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL7569477 | 0.92 | HDAC3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL7759484 | 0.92 | HDAC3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2157185-B1 | Process for production of succinic acid, and process for production of ammonium succinate solution | AJINOMOTO KK (JP) | 2014-05-14 | — | — | EP | claimed |
| US-8034975-B2 | Method of manufacturing succinic acid and ammonium succinate solutions | AJINOMOTO CO., INC. (JP) | 2011-10-11 | — | — | US | claimed |
| US-20100094051-A1 | METHOD OF MANUFACTURING SUCCINIC ACID AND AMMONIUM SUCCINATE SOLUTIONS | AJINOMOTO CO., INC. (JP) | 2010-04-15 | — | — | US | claimed |
| EP-2157185-A1 | PROCESS FOR PRODUCTION OF SUCCINIC ACID, AND PROCESS FOR PRODUCTION OF AMMONIUM SUCCINATE SOLUTION | Ajinomoto Co., Inc. (JP) | 2010-02-24 | — | — | EP | claimed |
| US-12043858-B2 | CO2 sequestration and creation of calcium carbonates through microbial induced carbonate precipitation | THE UNIVERSITY OF AKRON (US) | 2024-07-23 | — | — | US | disclosed |
| WO-2024039593-A1 | CALCIUM SUCCINATE MONOHYDRATE FORMULATION | BIOLINK LIFE SCIENCES, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024039593-A1 | CALCIUM SUCCINATE MONOHYDRATE FORMULATION | BIOLINK LIFE SCIENCES, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024039593-A1 | CALCIUM SUCCINATE MONOHYDRATE FORMULATION | BIOLINK LIFE SCIENCES, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| US-20240050388-A1 | CALCIUM SUCCINATE MONOHYDRATE FORMULATION | BIOLINK LIFE SCIENCES, INC. | 2024-02-15 | — | — | US | disclosed |
| US-20240050388-A1 | CALCIUM SUCCINATE MONOHYDRATE FORMULATION | BIOLINK LIFE SCIENCES, INC. | 2024-02-15 | — | — | US | disclosed |
| US-20240050388-A1 | CALCIUM SUCCINATE MONOHYDRATE FORMULATION | BIOLINK LIFE SCIENCES, INC. | 2024-02-15 | — | — | US | disclosed |
| US-20220002758-A1 | CO2 SEQUESTRATION AND CREATION OF CALCIUM CARBONATES THROUGH MICROBIAL INDUCED CARBONATE PRECIPITATION | THE UNIVERSITY OF AKRON | 2022-01-06 | — | — | US | disclosed |
| WO-2008143015-A1 | PROCESS FOR PRODUCTION OF SUCCINIC ACID, AND PROCESS FOR PRODUCTION OF AMMONIUM SUCCINATE SOLUTION | AJINOMOTO CO., INC. (JP) | 2008-11-27 | — | — | WO | disclosed |
| US-20070003672-A1 | Tri-part calcium fortified compositions and methods of making the same | COCO-COLA COMPANY | 2007-01-04 | — | — | US | disclosed |
| US-20070003671-A1 | Two-part calcium fortified compositions and methods of making the same | COCO-COLA COMPANY | 2007-01-04 | — | — | US | disclosed |
| US-6983798-B2 | Methods and fluid compositions for depositing and removing filter cake in a well bore | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-01-10 | — | — | US | disclosed |
| US-20050261137-A1 | Methods and fluid compositions for depositing and removing filter cake in a well bore | HALLIBURTON ENERGY SERVICES, INC. | 2005-11-24 | — | — | US | disclosed |
| EP-0249773-B1 | A PROCESS FOR THE PRODUCTION OF SUCCINIC ACID BY ANAEROBIC FERMENTATION | MICHIGAN BIOTECHNOLOGY INSTITUTE (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5143833-A | Anaerobiospirillum, controlling pH | EMERALD BIOAGRICULTURE CORPORATION | 1992-09-01 | — | — | US | disclosed |
| EP-0249773-A2 | A process for the production of succinic acid by anaerobic fermentation | MICHIGAN BIOTECHNOLOGY INSTITUTE (US) | 1987-12-23 | — | — | EP | disclosed |