Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CD74 | P04233 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180452 | 0.87 | MIF (0.63) | MIFIDO1PDE10AKMT2ACD74 | |
| SCHEMBL13164129 | 0.84 | MIF (0.50) | MIFIDO1PDE10AKMT2ACD74 | |
| SCHEMBL10160042 | 0.82 | MIF (0.48) | MIFIDO1PDE10AKMT2ACD74 | |
| SCHEMBL10210706 | 0.81 | IDO1 (0.50) | MIFIDO1PDE10AKMT2ACD74 | |
| SCHEMBL12124425 | 0.80 | TMEM97 (0.66) | — | |
| SCHEMBL14465204 | 0.79 | ASAH1 (0.41) | MIFIDO1PDE10AKMT2ACD74 | |
| SCHEMBL13367744 | 0.79 | MIF (0.66) | MIFKMT2ACD74MEN1POLB | |
| SCHEMBL6425871 | 0.78 | IDO1 (0.69) | IDO1ALDH1A1 | |
| SCHEMBL30336433 | 0.78 | SIGMAR1 (0.53) | MIFIDO1PDE10AKMT2ACD74 | |
| SCHEMBL616373 | 0.78 | SIGMAR1 (0.53) | MIFIDO1PDE10AKMT2ACD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063670-A1 | HETEROBICYCLIC MATRIX METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007139860-A2 | HETEROBICYLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |