Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MRE11 | P49959 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 4/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | MAX | P61244 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK3 | P49761 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186874 | 1.00 | MEN1 (0.57) | MEN1KMT2AMRE11POLBPIM1 | |
| SCHEMBL8181884 | 0.83 | PIM1 (0.52) | MEN1KMT2APOLBPIM1PIM2 | |
| SCHEMBL8181887 | 0.83 | PIM1 (0.52) | MEN1KMT2APOLBPIM1PIM2 | |
| SCHEMBL8181806 | 0.82 | PIM1 (0.67) | MEN1KMT2AMRE11POLBPIM1 | |
| SCHEMBL8181424 | 0.82 | PIM1 (0.67) | MEN1KMT2AMRE11POLBPIM1 | |
| SCHEMBL8181421 | 0.82 | PIM1 (0.67) | MEN1KMT2AMRE11POLBPIM1 | |
| SCHEMBL12685642 | 0.81 | PIM1 (0.71) | MEN1KMT2AMRE11POLBPIM1 | |
| SCHEMBL8172525 | 0.78 | HPGD (0.59) | MEN1KMT2APOLBPIM1PIM2 | |
| SCHEMBL8172523 | 0.78 | HPGD (0.59) | MEN1KMT2APOLBPIM1PIM2 | |
| SCHEMBL8186366 | 0.78 | PIM1 (0.77) | PIM1PIM2IGF1RNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |