Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186890 | 1.00 | MEN1 (0.46) | MEN1KMT2ANAMPTACHEBCHE | |
| SCHEMBL8188416 | 0.94 | MEN1 (0.46) | MEN1KMT2ANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8188423 | 0.94 | MEN1 (0.46) | MEN1KMT2ANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6979865 | 0.94 | ACHE (0.44) | NAMPTACHEBCHEHDAC1 | |
| SCHEMBL6979863 | 0.94 | ACHE (0.44) | NAMPTACHEBCHEHDAC1 | |
| SCHEMBL8185977 | 0.92 | ACHE (0.43) | KMT2ANAMPTACHEBCHEHDAC1 | |
| SCHEMBL8185979 | 0.92 | ACHE (0.43) | KMT2ANAMPTACHEBCHEHDAC1 | |
| SCHEMBL6983164 | 0.91 | ACHE (0.45) | NAMPTACHEBCHEHDAC1HDAC6 | |
| SCHEMBL6983168 | 0.91 | ACHE (0.45) | NAMPTACHEBCHEHDAC1HDAC6 | |
| SCHEMBL6985368 | 0.89 | HDAC1 (0.42) | NAMPTACHEBCHEALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073297-A1 | SUBSTITUTED INDOLINONE AS TYROSINE KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-12-07 | — | — | WO | disclosed |