SCHEMBL8187

SCHEMBL8187

NC(=O)C1=CN([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)C=CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 2/20 1.00
LMNA P02545 1/20 0.75
PMP22 Q01453 1/20 0.75
TP53 P04637 1/20 0.75
TSHR P16473 1/20 0.75
ALOX12 P18054 1/20 0.75
P2RY1 P47900 6/20 0.73
P2RY2 P41231 2/20 0.73
P2RX1 P51575 2/20 0.73
P2RX3 P56373 2/20 0.73
ALDH1A1 P00352 2/20 0.73
SRC P12931 1/20 0.73
P2RX4 Q99571 1/20 0.73
P2RX2 Q9UBL9 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
LDHA P00338 1/20 0.72
LDHB P07195 1/20 0.72
MACROD2 A1Z1Q3 1/20 0.69
SIRT6 Q8N6T7 1/20 0.69
MACROD1 Q9BQ69 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25792100 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL20202727 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL8188 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL29350404 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL1276381 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL8003782 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL29740660 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL29548827 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL29351291 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR
SCHEMBL27370819 1.00 ADH1A (1.00) ADH1ALMNAPMP22TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 93883 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144445-A1 MULTISPECTRAL IMAGING OF INTRINSIC METABOLIC FLUOROPHORES FOR THE IN-VIVO DETECTION OF HUMAN BREAST CANCER Philadelphia Lightwave, LLC (US) 2026-05-28 US claimed
EP-4749282-A2 HOMOGENOUS IMMUNOASSAY WITH COMPENSATION FOR BACKGROUND SIGNAL IDEXX Laboratories, Inc. (US) 2026-05-27 EP claimed
CN-122080225-A Fusion hydrogenase and application thereof 2026-05-26 CN claimed
CN-122082029-A Heterogeneous type electrocatalytic NADH regeneration catalyst and preparation method and application thereof 2026-05-26 CN claimed
CN-122071689-A Bayer Wiligam oxygenase mutant and application thereof 上海合全药业股份有限公司 2026-05-22 CN claimed
WO-2026104942-A1 BIOCATALYTIC SYNTHESIS OF ESTERS SOFT CHEMICALS S.R.L. (IT) 2026-05-21 WO claimed
WO-2026106725-A1 CHLOROPHYLL DERIVATIVES, CAROTENOID DERIVATIVES, AND DIETARY SUPPLEMENTS FOR HUMAN OCULAR HEALTH AND VISUAL PERFORMANCE RETINABIO, INC. (US) 2026-05-21 WO claimed
WO-2026106529-A1 NADP+-PRECURSOR AS ANTIAGING SUPPLEMENT DR CHARLES AB (SE) 2026-05-21 WO claimed
CN-122060589-A Marine in-situ microorganism culture and detection system based on fluorescence detection 海南大学 2026-05-19 CN claimed
CN-122038490-A Application of formate dehydrogenase and mutant thereof in reduction of carbon dioxide 浙江师范大学行知学院 2026-05-15 CN claimed
US-4117202-A SOLAR POWERED BIOLOGICAL FUEL CELL BECK TIMOTHY A 1978-09-26 US claimed
US-4097338-A Fluorimetric demonstration and determination of a reduced coenzyme or derivative in an aqueous system AKZONA INCORPORATED (US) 1978-06-27 US claimed
US-4066510-A ASSAY FOR MUTAGENESIS IN DIPLOID HUMAN LYMPHOBLASTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1978-01-03 US claimed
US-4045297-A Triglycerides determination method MONSANTO COMPANY (US) 1977-08-30 US claimed
US-4043872-A MALATE DEHYDROGENASE, TRIOSE PHOSPHATE ISOMERASE SYVA COMPANY (US) 1977-08-23 US claimed
US-4022667-A Substrate solution for carboxylic ester hydrolase determination THE UNIVERSITY OF ALABAMA (US) 1977-05-10 US claimed
US-4019961-A MULTISTAGE; NADH-REGENERATING SYSTEM BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-04-26 US claimed
US-4006061-A Lactate dehydrogenase determination method MONSANTO COMPANY (US) 1977-02-01 US claimed
US-4001089-A METHOD FOR DETERMINATION OF TRIGLYCERIDES AND GLYCEROL THE DOW CHEMICAL COMPANY (US) 1977-01-04 US claimed
US-3992158-A Integral analytical element EASTMAN KODAK COMPANY (US) 1976-11-16 US claimed