Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175915 | 0.91 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8192375 | 0.85 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8187093 | 0.82 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8177267 | 0.82 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL8205255 | 0.81 | PDE10A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28790784 | 0.75 | PDE4A (0.59) | PDE4AALDH1A1TARBP2GABRA2GABRB2 | |
| SCHEMBL12126901 | 0.75 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8191475 | 0.72 | PDE10A (0.42) | — | |
| SCHEMBL8185998 | 0.71 | PDE10A (0.41) | — | |
| SCHEMBL4330898 | 0.70 | PDE4A (0.59) | PDE4APDE4BALDH1A1TARBP2GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057330-A | USEFUL FOR THE PREVENTION AND TREATMENT OF A RESPIRATORY DISEASES REPRESENTED BY ASTHMA | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-5942515-A | RESPIRATORY SYSTEM DISORDERS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1999-08-24 | — | — | US | disclosed |