Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189448 | 0.89 | KDM4E (0.33) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8192800 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8186190 | 0.87 | KDM4E (0.38) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8185648 | 0.83 | KDM4E (0.37) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8191815 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8177278 | 0.82 | KDM4E (0.32) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8188147 | 0.82 | KDM4E (0.36) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8185453 | 0.81 | NPC1 (0.32) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8185997 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8187108 | 0.80 | HTT (0.33) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057330-A | USEFUL FOR THE PREVENTION AND TREATMENT OF A RESPIRATORY DISEASES REPRESENTED BY ASTHMA | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-5942515-A | RESPIRATORY SYSTEM DISORDERS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1999-08-24 | — | — | US | disclosed |