Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.48 |
| ▸ | DRD3 | P35462 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD1 | P21728 | 5/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | RET | P07949 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.48 |
| ▸ | HRH2 | P25021 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8186592 | 0.99 | SLC6A2 (0.49) | HRH1DRD3DRD2DRD1HRH3 | |
| SCHEMBL8177198 | 0.81 | DRD3 (0.60) | HRH1DRD3DRD2DRD1HRH3 | |
| Hydrochloric Acid SCHEMBL8177592 | 0.81 | DRD3 (0.59) | HRH1DRD3DRD2DRD1HRH3 | |
| SCHEMBL7611039 | 0.80 | CA12 (0.52) | HRH1DRD3DRD2DRD1HRH3 | |
| Hydrochloric Acid SCHEMBL8185083 | 0.79 | CA12 (0.51) | HRH1DRD3DRD2DRD1HRH3 | |
| SCHEMBL7603077 | 0.77 | HRH1 (0.46) | HRH1DRD3DRD2DRD1HRH3 | |
| SCHEMBL7603664 | 0.76 | HRH1 (0.45) | HRH1DRD3DRD2DRD1HRH3 | |
| SCHEMBL7605289 | 0.75 | HRH1 (0.45) | HRH1DRD3DRD2DRD1HRH3 | |
| Hydrochloric Acid SCHEMBL8186699 | 0.74 | HRH1 (0.45) | HRH1DRD3HRH3SLC6A2CYP1A2 | |
| SCHEMBL145501 | 0.74 | OPRM1 (0.61) | ADRA1AOPRK1KCNH2SLC6A4SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047673-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | EP | claimed |
| US-6048856-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-04-11 | — | — | US | claimed |
| WO-1999031058-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-06-24 | — | — | WO | claimed |
| EP-1047673-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | EP | disclosed |
| US-6048856-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-04-11 | — | — | US | disclosed |
| WO-1999031058-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-06-24 | — | — | WO | disclosed |