Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2B | P41595 | 5/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177254 | 0.99 | KMT2A (0.49) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8177215 | 0.84 | HTR2C (0.41) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8186128 | 0.83 | HTR2C (0.41) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8176828 | 0.82 | HTR2C (0.41) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8185910 | 0.81 | KMT2A (0.41) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8177219 | 0.80 | HTR2C (0.39) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8191899 | 0.80 | KMT2A (0.41) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8177229 | 0.79 | KMT2A (0.40) | KMT2AHTR2CHTR2AHTR2BACVR1 | |
| SCHEMBL8187118 | 0.79 | PDE4A (0.47) | KMT2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL8175991 | 0.78 | HTR2C (0.40) | KMT2AHTR2CHTR2AHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057330-A | USEFUL FOR THE PREVENTION AND TREATMENT OF A RESPIRATORY DISEASES REPRESENTED BY ASTHMA | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-05-02 | — | — | US | disclosed |