Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991511 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL8077136 | 0.82 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6990094 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6331760 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213125 | 0.75 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL7839456 | 0.75 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8080224 | 0.73 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8080218 | 0.73 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL6989030 | 0.73 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL8182646 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066667-A | COMPOUNDS OF GENERAL FORMULA 3,4-DI(SUBSTITUTED PHENYL),5-AMINOALKYL,5-CARBOXYALKYL-FURAN-2-ONE; ADMINISTERING TO TREAT PAIN, ARTHRITIS | ASHBROOK CHARLES D (US) | 2000-05-23 | — | — | US | claimed |
| US-6066667-A | COMPOUNDS OF GENERAL FORMULA 3,4-DI(SUBSTITUTED PHENYL),5-AMINOALKYL,5-CARBOXYALKYL-FURAN-2-ONE; ADMINISTERING TO TREAT PAIN, ARTHRITIS | ASHBROOK CHARLES D (US) | 2000-05-23 | — | — | US | disclosed |