Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.54 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.54 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.54 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.54 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.49 |
| ▸ | CDC25B | P30305 | 8/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666776 | 1.00 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8596281 | 1.00 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8189067 | 1.00 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6891433 | 0.99 | SSTR1 (0.56) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6428119 | 0.99 | SSTR1 (0.56) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6889751 | 0.99 | SSTR1 (0.56) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6809789 | 0.88 | SSTR1 (0.59) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6544934 | 0.88 | SSTR1 (0.59) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL977853 | 0.88 | SSTR1 (0.59) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL990411 | 0.88 | SSTR1 (0.59) | NT5ESSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093698-A | 1-(2',3',5'-TRIACETYL-BETA-D-RIBOFURANOSYL),2-BROMO,5,6-DICHLORO -BENZIMIDAZOLE OR 1-(5'-ACETYL-BETA-D-RIBOFURANOSYL),2-BROMO,5,6-DICHLORO-BENZIMIDAZOLE; TREATING HERPES VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-07-25 | — | — | US | disclosed |
| US-5712255-A | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-27 | — | — | US | disclosed |
| US-5705490-A | TREATMENT OF HERPES OR CYTOMEGALOVIRUS WITH BENZIMIDAZOLE DERIATIVES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-06 | — | — | US | disclosed |
| US-5665709-A | FOR TREATING A HERPES VIRAL INFECTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-09-09 | — | — | US | disclosed |
| US-5654283-A | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-08-05 | — | — | US | disclosed |
| US-5646125-A | Polysubstituted benzimidazoles as antiviral agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-07-08 | — | — | US | disclosed |
| US-5574058-A | Polysubstituted benzimidazoles as antiviral agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-11-12 | — | — | US | disclosed |
| US-5360795-A | Treating cytomegalo virus and herpes simplex viruses | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1994-11-01 | — | — | US | disclosed |