Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 3/20 | 0.59 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.59 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.59 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.59 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.59 |
| ▸ | CDC25B | P30305 | 8/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.59 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809789 | 1.00 | SSTR1 (0.59) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL990411 | 1.00 | SSTR1 (0.59) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6544934 | 1.00 | SSTR1 (0.59) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL20473783 | 0.92 | PTPN1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL20473798 | 0.92 | SSTR1 (0.55) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL19400292 | 0.92 | SSTR1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8729050 | 0.91 | SSTR1 (0.57) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6513373 | 0.91 | PTPN1 (0.56) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL24739211 | 0.90 | SSTR1 (0.69) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL22927975 | 0.90 | SSTR1 (0.69) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720889-B1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LTD (AU) | 2014-11-26 | — | — | EP | disclosed |
| US-8173606-B2 | Sulfated oligosaccharide derivatives | PROGEN PHARMACEUTICALS LIMITED (AU) | 2012-05-08 | — | — | US | disclosed |
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LIMITED (AU) | 2011-06-02 | — | — | US | disclosed |
| US-7875592-B2 | inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease | PROGEN PHARMACEUTICALS LIMITED (AU) | 2011-01-25 | — | — | US | disclosed |
| EP-1720889-A4 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LTD (AU) | 2008-03-19 | — | — | EP | disclosed |
| US-20070185037-A1 | Sulfated oligosaccharide derivatives | PROGEN INDUSTRIES LIMITED (AU) | 2007-08-09 | — | — | US | disclosed |
| EP-1720889-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | Progen Industries Limited (AU) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005085264-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN INDUSTRIES LIMITED (AU) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185037-A1 | Sulfated oligosaccharide derivatives | HPSE, APOB, LIPG | SSTR1 3599/4885SSTR2 3307/4885SSTR4 2974/4885 |
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | HPSE, APOB, LIPG | SSTR1 3599/4885SSTR2 3307/4885SSTR4 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.