Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965444 | 0.68 | — | — | |
| SCHEMBL8384669 | 0.65 | TSHR (0.44) | ALDH1A1TSHRHIF1A | |
| Pivalate SCHEMBL9630884 | 0.63 | TSHR (0.42) | ALDH1A1TSHRHIF1A | |
| SCHEMBL3670503 | 0.63 | TSHR (0.42) | ALDH1A1TSHRHIF1A | |
| Pivalate SCHEMBL27720186 | 0.62 | — | — | |
| SCHEMBL7759825 | 0.61 | TSHR (0.40) | ALDH1A1TSHRHIF1A | |
| SCHEMBL7761713 | 0.61 | TSHR (0.40) | ALDH1A1TSHRHIF1A | |
| SCHEMBL16449145 | 0.61 | TSHR (0.40) | ALDH1A1TSHRHIF1A | |
| SCHEMBL9600163 | 0.59 | TSHR (0.38) | ALDH1A1TSHRHIF1A | |
| Pivalate SCHEMBL31257189 | 0.59 | TSHR (0.38) | ALDH1A1TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020519-A | Diphenyl-cyclopropenes as selective K-agonists | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| US-5968968-A | Diphenyl-cyclopropenes as selective K-agonists | WARNER-LAMBERT COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1998003491-A1 | DIPHENYL-CYCLOPROPENES AS SELECTIVE K-AGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |