SCHEMBL8384669

SCHEMBL8384669

CC(C=O)(C(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
TP53 P04637 2/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
ACLY P53396 1/20 0.31
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28809280 0.79 DGAT1 (0.38) TSHRALDH1A1
SCHEMBL1255436 0.73
SCHEMBL1289474 0.73
SCHEMBL3670503 0.71 TSHR (0.42) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL11518474 0.71
SCHEMBL5730796 0.71
SCHEMBL3592420 0.71
SCHEMBL7202469 0.71
Pivalate SCHEMBL27720186 0.70
Pivalate SCHEMBL27325303 0.69 TSHR (0.47) TSHRALDH1A1CYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP claimed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP claimed
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
US-5112743-A Aromatic-aldehyde diazo resins FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP disclosed