Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.45 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.45 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.45 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675748 | 0.88 | FFAR1 (0.53) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL2310765 | 0.81 | FFAR1 (0.53) | MAOBCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL8016866 | 0.81 | CYP11B1 (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19ABL1 | |
| SCHEMBL30830335 | 0.81 | CYP11B1 (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19ABL1 | |
| SCHEMBL16057815 | 0.81 | ESR2 (0.44) | FFAR1SLC9A1MMP2MMP3CNR1 | |
| SCHEMBL4937029 | 0.80 | FYN (0.56) | MAOBCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL15413958 | 0.80 | ESR2 (0.60) | — | |
| SCHEMBL14850870 | 0.79 | ACHE (0.57) | MAOBCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL31222693 | 0.79 | MAOB (0.66) | MAOBCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL2604700 | 0.79 | MAOB (0.66) | MAOBCYP1A1CYP1A2CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080870-A | Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-06-27 | — | — | US | disclosed |