SCHEMBL8189488

SCHEMBL8189488

CC(C)(COc1ccc(N)c(C(F)(F)F)c1)COc1ccc(N)c(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
AR P10275 1/20 0.39
CYP2C9 P11712 2/20 0.37
CYP17A1 P05093 1/20 0.37
CYP2C19 P33261 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 2/20 0.37
USP2 O75604 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
THRB P10828 1/20 0.37
G6PD P11413 1/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4230857 0.83 KMT2A (0.54) FFAR4MAPTALDH1A1ARMEN1
Hydrochloric Acid SCHEMBL185985 0.81 KMT2A (0.53) FFAR4MAPTALDH1A1ARMEN1
SCHEMBL10269779 0.80 THRA (0.48) FFAR4MAPTCYP2C9CYP2C19MEN1
SCHEMBL10352007 0.80 MAPT (0.48) FFAR4MAPTALDH1A1MEN1KMT2A
SCHEMBL10352711 0.79 FFAR4 (0.43) FFAR4MAPTALDH1A1ARCYP2C9
Dimethylamine SCHEMBL6718739 0.79 KMT2A (0.50) FFAR4MAPTALDH1A1ARMEN1
SCHEMBL10352869 0.79 PDK2 (0.44) FFAR4MAPTALDH1A1ARCYP2C9
SCHEMBL10352006 0.78 THRA (0.52) MAPTCYP2C9CYP2C19THRBALOX15
SCHEMBL8180147 0.77 NPC1 (0.47) MAPTALDH1A1ARMEN1KMT2A
SCHEMBL77088 0.77 FFAR4 (0.56) FFAR4MAPTALDH1A1ARMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6051722-A PRECURSOR FOR POLYIMIDE COPOLYMER; USABLE IN OPTICAL LONG-DISTANCE COMMUNICATION, SIGNAL PROCESSING, PHOTOELECTRIC HYBRID CIRCUITS AND OPTICAL COMPUTERS HITACHI CHEMICAL COMPANY, LTD. (JP) 2000-04-18 US disclosed