SCHEMBL818949

SCHEMBL818949

CC=[Zr](Br)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
HTR2A P28223 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CHRM2 P08172 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
NFKB1 P19838 1/20 0.34
CHRM3 P20309 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
THPO P40225 1/20 0.34
OPRK1 P41145 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5839767 0.81 RET (0.34) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL3381116 0.80 HTR2A (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL615607 0.80 HTR2A (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL9519063 0.80 HTR6 (0.33) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL716021 0.80 HTR6 (0.33) KDM4EHTR2ALMNATP53CHRM2
Propene SCHEMBL1924094 0.76 KDM4E (0.33) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL6857385 0.76 RET (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL29697103 0.76 HTR2A (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL3685967 0.76 HTR2A (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL29480066 0.76 RET (0.38) KDM4EHTR2ALMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-10793652-B2 Solid PMAO composition and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-10-06 US disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
EP-3318544-B1 PROCESS FOR THE PREPARATION OF POLYMERIZED POLYETHYLENE WAX SCG CHEMICALS CO LTD (TH) 2020-03-18 EP disclosed
US-20190263947-A1 PROCESS FOR THE PREPARATION OF POLYMERIZED POLYETHYLENE WAX SCG CHEMICALS CO., LTD. (TH) 2019-08-29 US disclosed
US-20190153127-A1 SOLID PMAO COMPOSITION AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2019-05-23 US disclosed
EP-3480258-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2019-05-08 EP disclosed
EP-3441406-A1 SOLID PMAO COMPOSITION AND METHOD FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2019-02-13 EP disclosed
US-20180355077-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2018-12-13 US disclosed
EP-2570437-B1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN TOSOH FINECHEM CORP (JP) 2018-07-04 EP disclosed
EP-2360191-A1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND PROCESS FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2011-08-24 EP disclosed
US-7910764-B2 Polymethylaluminoxane preparation, method of producing the same, polymerization catalyst, and polymerization method of olefins TOSOH FINECHEM CORPORATION (JP) 2011-03-22 US disclosed
US-20070197745-A1 Polymethylaluminoxane preparation, method of producing the same, polymerization catalyst, and polymerization method of olefins TOSOH FINECHEM CORPORATION (JP) 2007-08-23 US disclosed
EP-1728795-A1 POLYMETHYLALUMINOXANE PRODUCT, PROCESS FOR PRODUCING THE SAME, POLYMERIZATION CATALYST, AND METHOD OF POLYMERIZING OLEFIN Tosoh Finechem Corporation (JP) 2006-12-06 EP disclosed
US-6881695-B2 Olefin polymerization catalyst and method for producing modified methylaluminoxane for use as olefin polymerization catalyst TOSOH FINECHEM CORPORATION (JP) 2005-04-19 US disclosed
US-20030195307-A1 Olefin polymerization catalyst and method for producing modified methylaluminoxane for use as olefin polymerization catalyst TOSOH FINECHEM CORPORATION (JP) 2003-10-16 US disclosed
EP-1352913-A1 Preparation of modified methylaluminoxane olefin polymerisation catalyst component Tosoh Finechem Corporation (JP) 2003-10-15 EP disclosed
EP-0285443-B1 PROCESS FOR PRODUCING SOLID CATALYST FOR POLYMERIZATION OF OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-01-08 EP disclosed
US-4874734-A USING SOLUTION OF ALUMINOXANE, PARTICULATE CARRIER WITH TRANSITION METAL COMPOUND, SOLVENT IN WHICH ALUMINOXANE IS INSOLUBLE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-10-17 US disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed