Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285805 | 0.77 | C1R (0.39) | C1R | |
| SCHEMBL22650909 | 0.70 | CRBN (0.38) | HPGDPARP1PARP10PARP11 | |
| SCHEMBL12552450 | 0.70 | METAP1 (0.36) | C1R | |
| SCHEMBL14267621 | 0.66 | MAPK13 (0.33) | — | |
| SCHEMBL12811256 | 0.63 | C1R (0.45) | C1R | |
| SCHEMBL15241514 | 0.62 | — | — | |
| SCHEMBL29893980 | 0.61 | MAPT (0.44) | C1R | |
| SCHEMBL3838727 | 0.61 | MAPT (0.44) | C1R | |
| SCHEMBL27262734 | 0.61 | C1R (0.45) | C1R | |
| SCHEMBL8562544 | 0.61 | HPGD (0.35) | HPGDPDPK1PARP1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360800-A | Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives | GLAXO GROUP LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| EP-0306323-A2 | Lactam derivatives | GLAXO GROUP LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |