Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12552450 | 0.71 | METAP1 (0.36) | C1R | |
| SCHEMBL10495047 | 0.69 | MT-CO2 (0.45) | MT-CO2POLBMAPT | |
| SCHEMBL12811256 | 0.64 | C1R (0.45) | C1R | |
| SCHEMBL9573718 | 0.63 | MT-CO2 (0.47) | MT-CO2POLBMAPT | |
| SCHEMBL29893980 | 0.62 | MAPT (0.44) | C1RMAPT | |
| SCHEMBL3838727 | 0.62 | MAPT (0.44) | C1RMAPT | |
| SCHEMBL11291211 | 0.61 | MT-CO2 (0.41) | MT-CO2POLBMAPT | |
| SCHEMBL7291543 | 0.61 | MT-CO2 (0.49) | C1RMT-CO2POLBMAPT | |
| SCHEMBL3201693 | 0.61 | — | — | |
| SCHEMBL26756570 | 0.61 | APP (0.38) | C1RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144174-A1 | DEUTERIUM-ENRICHED ODANSETRON | PROTIA, LLC (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110144174-A1 | DEUTERIUM-ENRICHED ODANSETRON | PROTIA, LLC (US) | 2011-06-16 | — | — | US | disclosed |
| US-7919516-B2 | Deuterium-enriched ondansetron | PROTIA, LLC (US) | 2011-04-05 | — | — | US | disclosed |
| US-7919516-B2 | Deuterium-enriched ondansetron | PROTIA, LLC (US) | 2011-04-05 | — | — | US | disclosed |
| US-20090076107-A1 | DEUTERIUM-ENRICHED ODANSETRON | PROTIA, LLC (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076107-A1 | DEUTERIUM-ENRICHED ODANSETRON | PROTIA, LLC (US) | 2009-03-19 | — | — | US | disclosed |
| EP-0221629-B1 | PROCESS FOR THE PREPARATION OF 3-IMIDAZOLYLMETHYLTETRAHYDROCARBAZOLONES | GLAXO GROUP LIMITED (GB) | 1992-03-11 | — | — | EP | disclosed |
| US-4957609-A | CYCLIZATION | GLAXO GROUP LIMITED (GB) | 1990-09-18 | — | — | US | disclosed |
| EP-0221629-A1 | Process for the preparation of 3-imidazolylmethyltetrahydrocarbazolones | GLAXO GROUP LIMITED (GB) | 1987-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144174-A1 | DEUTERIUM-ENRICHED ODANSETRON | SLC6A3, DRD2, AVPR2 | C1R 4567/4885MT-CO2 4163/4885POLB 3620/4885 |
| US-20090076107-A1 | DEUTERIUM-ENRICHED ODANSETRON | SLC6A3, DRD2, AVPR2 | C1R 4567/4885MT-CO2 4163/4885POLB 3620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.