SCHEMBL819037

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30390791	1.00	THRB (0.49)	THRBESR1ESR2ALDH1A1TSHR
	SCHEMBL29720691	0.90	THRB (0.46)	THRBESR1ESR2ALDH1A1TSHR
	SCHEMBL556299	0.90	THRB (0.46)	THRBESR1ESR2ALDH1A1TSHR
	SCHEMBL29720690	0.89	THRB (0.45)	THRBESR1ESR2ALDH1A1TSHR
	SCHEMBL557484	0.89	THRB (0.45)	THRBESR1ESR2ALDH1A1TSHR
	SCHEMBL2234000	0.89	THRB (0.48)	THRBALDH1A1MEN1KMT2APOLB
	SCHEMBL15356206	0.85	THRB (0.42)	THRBESR1ESR2TSHRMEN1
	SCHEMBL15356202	0.85	THRB (0.50)	THRBESR1ESR2ALDH1A1TSHR
	SCHEMBL14066386	0.84	ESR1 (0.38)	ESR1ESR2TSHRMEN1KMT2A
	SCHEMBL40434	0.84	THRB (0.63)	THRBALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.